glioblastoma part ii molecular targets and clinical trials an issue of neurosurgery clinics of north america

This issue of Neurosurgery Clinics, guest edited by Dr. Linda M. Liau, is dedicated to Glioblastoma: Molecular and Clinical Trials. This issue is one of four selected each year by the series consulting editors, Drs. Russell R. Lonser and Daniel K. Resnick. Topics will include-but are not limited to-Pathology & Molecular Markers, Cellular States & Genetic Diversity in Glioblastoma, Mismatch Repair in Glioblastoma Resistance, Genetic Susceptibility in Brain Cancer, Pediatric Gliomas: Molecular Landscape & Emerging Targets, Molecularly Targeted Clinical Trials, Novel Radiation Sensitizers, Immunotherapy Checkpoint Inhibitors, Brain Tumor Vaccines, CAR T Cells, Oncolytic Virotherapy, Targeting Cancer Stem Cells, Therapeutic Delivery to CNS, Theranostics: Dual Modality PET Tracers, and Neuroimaging & Novel Response Assessments.

Objev podobné jako Glioblastoma, Part II: Molecular Targets and Clinical Trials, An Issue of Neurosurgery Clinics of North America

In this issue of Medical Clinics of North America, guest editors Dr. Jeffrey Turner and Ursula Brewster bring their considerable expertise to the topic of An Update in Nephrology. Top experts in the field provide timely updates in CKD, kidney disease, kidney health, renal replacement therapy, and treatments. Contains 12 practice-oriented topics including diagnosis of CKD and assessing eGFR; diabetic nephropathy; pregnancy in CKD: AKI in pregnant women and management of CKD in the pregnant patient; onco-nephrology; and more. Provides in-depth clinical reviews on nephrology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.Â

Objev podobné jako An Update in Nephrology, An Issue of Medical Clinics of North America

In this issue of Veterinary Clinics: Small Animal Practice, guest editor Lisa Powell brings her considerable expertise to the topic of Hot Topics in Small Animal Medicine. This issue is an eclectic compilation of some of the most popular topics among readers of this Clinics series. Top experts in the field provide updates on the latest advances and developments in several key areas of importance for small animal practitioners. Contains a variety of relevant, practice-oriented topics including urinary tract infection treatment and comparative therapeutics; acute kidney injury in dogs and cats; fluid and electrolyte therapy during vomiting and diarrhea; basics of mechanical ventilation for dogs and cats; fluid therapy for the emergent small animal patient: crystalloids, colloids, and albumin products; and more. Provides in-depth clinical reviews on hot topics in small animal medicine, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Objev podobné jako Hot Topics in Small Animal Medicine, An Issue of Veterinary Clinics of North America: Small Animal Practice

historický román 18. století Skotsko Amerika
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expediční hra Jižní Amerika
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povlečení s motivem Elsa a Anna
koupelnové textilie Tom Tailor Home of Colors

In this issue of Sleep Medicine Clinics, guest editors Drs. Michelle Cao and Sunil Sharma bring their considerable expertise to the topic of Hospital Sleep Medicine and Non-Invasive Ventilation. Inpatient sleep medicine consultation service is a new subspecialty that can greatly enhance the care of patients with complex sleep related respiratory disorders as well as provide a smooth transition to outpatient management. Many common sleep-related respiratory conditions are encountered in the hospital setting, and these patients benefit from specialized inpatient management by experts in pulmonology and sleep medicine. Contains 14 relevant, practice-oriented topics including heart failure and CSA; cardiac arrhythmias and sleep disorders; non-invasive ventilation in ALS; obesity hypoventilation syndrome; hypercapnic COPD and overlap syndrome; opioids and respiratory-related consequences; and moreProvides in-depth clinical reviews on hospital sleep medicine and non-invasive ventilation, offering actionable insights for clinical practicePresents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews

Objev podobné jako Hospital Sleep Medicine and Non-Invasive Ventilation: Emerging Clinical Paradigm, An Issue of Sleep Medicine Clinics

In this issue of Clinics in Liver Disease, guest editor Dr. David Bernstein brings his considerable expertise to the topic of The Liver and Renal Disease. The presence of liver disease in patients with chronic renal disease makes the management of both conditions more challenging. In this issue, top experts in the field address many aspects of the treatment and management of these co-existing conditions. Contains 13 relevant, practice-oriented topics including hyponatremia in cirrhosis; pathophysiology of hepatorenal syndrome; definitions, diagnosis, and management of hepatorenal syndrome; renal replacement therapy in patients with acute liver failure and end-stage cirrhosis awaiting liver transplant; simultaneous liver/kidney transplantation; and more. Provides in-depth clinical reviews on the liver and renal disease, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.Â

Objev podobné jako The Liver and Renal Disease, An Issue of Clinics in Liver Disease

In this issue of Cardiology Clinics, guest editors Drs. Sharmila Dorbala and Piotr Slomka bring their considerable expertise to the topic of Nuclear Cardiology. Top experts in the field cover key topics such as advances in single-photon emission computed tomography hardware and software; technical aspects of cardiac PET; novel PET applications and radiotracers of imaging cardiovascular pathophysiology; radionuclide tracers for myocardial perfusion imaging and blood flow quantification; and more. Contains 16 relevant, practice-oriented topics including artificial intelligence in nuclear cardiology; what is new in risk assessment in nuclear cardiology; radionuclide assessments and imaging for various conditions; low radiation dose myocardial perfusion imaging; myocardial perfusion imaging with calcium score; and moreProvides in-depth clinical reviews on nuclear cardiology, offering actionable insights for clinical practicePresents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews

Objev podobné jako Nuclear Cardiology, An Issue of Cardiology Clinics

In this issue of Endocrinology and Metabolism Clinics, guest editors Drs. Jacqueline Jonklaas and Kenneth Burman bring their considerable expertise to the topic of Thyroid Cancer Update. Top experts in the field cover novel treatments, screening strategies, and management, along with topics about survivorship and quality of life. Contains 14 relevant, practice-oriented topics including update in papillary thyroid cancer; optimum treatment for medullary thyroid cancer; MEN1/MEN2/familial thyroid cancer; the financial burden of thyroid cancer; and moreProvides in-depth clinical reviews on thyroid cancer, offering actionable insights for clinical practicePresents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews

Objev podobné jako Thyroid Cancer Update, An Issue of Endocrinology and Metabolism Clinics of North America

In this issue of Facial Plastic Surgery Clinics, guest editor Dr. Dean M. Toriumi brings his considerable expertise to the topic of Preservation Rhinoplasty Merges with Structure Rhinoplasty. Top experts in the field, some who prefer a preservation rhinoplasty approach and some who utilize reduction techniques, provide readers with articles that contrast the two approaches and offer expert content about both techniques. Contains 15 practice-oriented topics including surface techniques in dorsal preservation; open preservation rhinoplasty using the Piezotome; modified dorsal split technique; managing the severe septal deviation using dorsal preservation; push up for correction of the saddle nose deformity; Brazilian approach to dorsal preservation; and more. Provides in-depth clinical reviews on preservation rhinoplasty and structure rhinoplasty, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.Â

Objev podobné jako Preservation Rhinoplasty Merges with Structure Rhinoplasty, An Issue of Facial Plastic Surgery Clinics of North America

In this issue of Cardiac Electrophysiology Clinics, guest editors Drs. Tolga Aksu and Olujimi A. Ajijola bring their considerable expertise to the topic of Autonomic Nervous System and Arrhythmias. Top experts in the field discuss topics such as the role of ANS in atrial fibrillation; the role of ANS in VVS and clinical bradyarrhythmias; the role of ANS in ventricular arrhythmias; pathophysiologic mechanisms in cardiac ANS and arrhythmias; cardiac neuroanatomy; and more.Contains 15 relevant, practice-oriented topics including non-invasive neuromodulation of arrhythmias; experimental neuromodulation of the cardiac ANS; the role of ANS in cardio-renal syndrome; device-based therapies for cardiac neuromodulation; and more.Provides in-depth clinical reviews on the autonomic nervous system and arrhythmias, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Objev podobné jako Autonomic Nervous System and Arrhythmias, An Issue of Cardiac Electrophysiology Clinics

In this issue of Physician Assistant Clinics, guest editor Diane Bruessow of Yale School of Medicine brings her considerable expertise to the topic of Gender Minority Medicine. Filling a knowledge gap in transgender health in primary care, this issue features articles by top experts that focus on up-to-date standards regarding clinical care, hormone therapy, inclusion, hormone therapy and surgery, and more. Contains 12 relevant, practice-oriented topics including interpreting gendered lab results; deferring puberty in transgender adolescents and associated clinical care; administrative considerations (or creating a welcoming environment) for transgender inclusion; navigating transgender health in the uniformed services; and more. Provides in-depth clinical reviews on gender minority medicine, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Objev podobné jako Gender Minority Medicine, An Issue of Physician Assistant Clinics

In this issue of Clinics in Sports Medicine, guest editor Dr. Ashley M. Shilling brings her considerable expertise to the topic of Sports Anesthesia. Top experts in the field focus on anesthesia approaches specifically for athletes and orthopaedic sports injuries, including unique medical considerations, pain management tactics for athletes, and more. Contains 14 relevant, practice-oriented topics including anesthesia for the patient undergoing hip arthroscopy; local anesthetics, liposomal anesthetics, and toxicity; pain management in the elite athlete; managing the complex pain patient through total joint arthroplasty; managing chronic pain following total joint arthroplasty; and more. Provides in-depth clinical reviews on sports anesthesia, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.Â

Objev podobné jako Sports Anesthesia, An Issue of Clinics in Sports Medicine

Regulatory bodies such as the European Medicine Agency have done tremendous work in collaboration with experts from the field to develop Good Clinical Practices that apply not only in Europe but also in emerging countries. Designed to be a teaching aid and reference guide, A Practical Guide to Human Research and Clinical focuses on ethics, regulations, and guidelines.Conducting a successful clinical trial requires not only a strong basic knowledge, but also hands-on practical training. The book explains the intricate details of the subject to readers by citing concrete cases, exercises, and templates along with the theoretical aspects. Prof. M.U.R Naidu and his co-authors address all aspects of clinical trials from clinical research, drug development, and quality to methodology, biostatistics, and pharmacovigilance.

Objev podobné jako A Practical Guide to Human Research and Clinical Trials - M. U. R. Naidu, P. Usha Rani

The ultimate book of running adventures across North America featuring 200 epic routes from city circuits to off-road trails plus amazing running stories from celebrated athletes.Discover tales of 50 incredible runs plus a further 150 awesome running trip ideas from easy-going jogs to one-of-a-kind challenges. Epic Runs of North America takes travelers across the US, Canada, and the Caribbean to experience heart-pounding trails that are a tonic for the mind, soul - and legs! Inside Epic Runs of North America:50 first-person accounts of running routes, races and trails plus 150 suggestions of similar runs to experienceRemarkable storiesfrom celebrated athletes and writers offering personal insights into runs they''ve completed including Mark Remy, Hannah Selinger, Jinghuah Liu Tervalon, Stephanie Case, Alison Mariella Désir, Barbara Noe Kennedy, Brendan Sainsbury, Brian Metzler, Charlie Engle, Matt Phillips, and moreChallenge level grading for each run varies from easy for running newbies, harder for runners seeking a challenge, and epic for seasoned racersBreathtaking photography that brings each run to life and inspires readers to explore the worldExpert information, maps and practical details on where to start and finish your run, total distance, how to get there, what to take, where to stay, and things to knowBeautiful and ... Unknown localization key: "more"

Objev podobné jako Lonely Planet Epic Runs of North America - Lonely Planet, Alison Mariella Desir, Stephanie Case, Michael Wardian, Mark Remy, Jinghuan Liu Tervalon, Ci

A lavishly illustrated, large-format reference book by two preeminent experts on North American shorebirdsMore than half a century has passed since the publication of The Shorebirds of North America, Peter Matthiessen’s masterful natural history of what is arguably the world’s most amazing and specialized bird group. In the intervening decades, our knowledge about these birds has grown significantly, as have the threats to their populations and habitats. Pete Dunne and Kevin Karlson celebrate Matthiessen’s classic book with this updated and expanded natural history of North American shorebirds. This elegantly written book begins by introducing readers to the unrivaled splendor of shorebirds and goes on to cover topics ranging from their biology and habitats to courtship and breeding, flight, the perils of migration, and conservation. Detailed accounts convey the richness and variety of the five family groups, with incisive, fact-filled descriptions of all 52 species of shorebirds known to breed in North America. Featuring hundreds of breathtaking images by Karlson and other photographers and drawing on the latest science, The Shorebirds of North America is a worthy tribute to Matthiessen’s enduring work and an indispensable reference for bird lovers everywhere.

Objev podobné jako The Shorebirds of North America - Pete Dunne, Kevin T. Karlson

The most up-to-date and gorgeous photographic collection of all 1,144 bird species in North America (including Hawaii!). A Great Blue Heron, a Wood Duck, a Baltimore Oriole, an Eastern Bluebird, or a Belted Kingfisher—which North American bird species is your favorite? In Birds of North America: A Photographic Atlas, Bruce M. Beehler provides the information and images you need to identify and enjoy each of the 1,144 amazing and diverse bird species recorded in the United States and Canada, including Hawaii and Alaska. Featuring more than 1,200 full-color photographs and illustrations and more than 700 range maps, this comprehensive reference provides both beginners and seasoned birders with important facts about each bird's ecology, behavior, seasonal movements, nesting biology, and conservation status. Birds of North America gives bird-lovers everything they could ask for: The photographs and illustrations, selected and curated by Brian E. Small, one of America's most talented nature photographers, depict each species in its most beautiful plumage and natural habitat. The largest, most detailed, and most up-to-date range maps available anywhere provide invaluable insider information on the best birding hotspots. And the special sections rounding out the book offer helpful guidance on birding gear, field trip planning, critical resources, ... Unknown localization key: "more"

Objev podobné jako Birds of North America - Bruce M. Beehler

An engaging and visually exciting look at some of North America''s major citiesThis series offers readers of 9 and up an engaging and visually exciting look at some of the world''s major cities. Cityscapes draw in the reader with facts about the iconic buildings that help to shape each city''s unique identity. Data-packed pages give the essential details about each featured city, including where to go, what to do and things to eat on a visit, as well as information about the city''s history. The cities of North America covered in the book are Mexico City, Mexico; Toronto, Canada; New York, USA; Havana, Cuba; Montreal, Canada; Nuuk, Greenland; Washington D.C, USA; Managua, Nicaragua; San Francisco, USA; Guatemala City, Guatemala; Ottawa, Canada; San Juan, Puerto Rico; Kingston, Jamaica; Calgary, Canada; Las Vegas, USA; Chicago, USA; Port-au-Prince, Haiti and Tegucigalpa, Honduras.Titles in the 6-book series feature the cities of Africa, Asia, Australasia, Europe, North America and South America.

Objev podobné jako Cities of the World: Cities of North America - Rob Hunt

Get to know black bears, brown bears, and polar bears like never before—through Stan Tekiela’s wildlife photography, personal anecdotes, and years of research. They are icons of our wild places. They are powerful and intimidating, yet they signify calmness, comfort, and peace. Bears are adored around the world. They are magnificent animals that capture our fascination. Enter the world of bears with award-winning author, naturalist, and wildlife photographer Stan Tekiela. Crawling into black bear dens in northern Wisconsin, trekking across the Manitoba tundra in search of polar bears, traversing the Rocky Mountains in pursuit of grizzly bears, Stan spent more than 20 years traveling across the United States and Canada to observe and photograph bears. He documented every aspect of their lives: major events such as mating and hibernation (torpor), as well as everyday activities including foraging, hunting, and socializing. The result is a striking portrayal of these mammals in Bears of North America. Stan’s extraordinary photographs depict the creatures in a new, unique fashion. The coffee-table book is pleasurable to browse and easy to read. Accompany Stan on some of the greatest adventures of his life. Explore North America’s desolate areas with him, pursuing these resourceful animals. With his ... Unknown localization key: "more"

Objev podobné jako Bears of North America - Stan Tekiela

This book offers a visual journey through the history of North America via a series of engaging, detailed maps, explaining key events and eras from prehistory to the 21st century. Specially commissioned maps tell the story of this vast region: the first human populations; the complex, ancient civilizations that arose; later Indigenous peoples and their societies; the first Westerners to arrive on the shores, from the Vikings to the Mayflower; early European settlements and their devastating effects; the stories of enslaved people and the abolition of slavery; the American Revolution and Civil War that shaped the modern United States; the Mexican-American War; the founding of Canada; and birth of the modern era and beyond. Brand new maps are accompanied by historic maps, documents, and artefacts, while timelines clearly lay out the chronology of events. Each era is introduced and explained, while features offer a closer look at selected moments. Whether for casual browsing or a deep dive into the past, History of North America Map by Map is essential reading for anyone who wants to know more about this fascinating land.

Objev podobné jako History of North America Map by Map - DK

Nature's Treasures of North America is a brilliant exploration of some of the habitats of North America—the coast, mountains, plains, woodlands, deserts, and lakes—as well as the animals that live there. Explore woodlands and forests, home to animals like the Northern spotted owl and the bobcat, or the great plains, where you'll find wildflowers such as chicory and buttercup and animals like bison. Or even the desert, with its cacti, iguanas, and kit foxes. Find all of this and more in this beautifully illustrated guide.

Objev podobné jako Nature's Treasures of North America - Alison Limentani

A must-have reference for any nature lover: The most comprehensive and authoritative guide to the mushrooms of North America, updated for the first time in decades to reflect the impact of climate change and the advancements in DNA sequencing that have radically altered the classification process.Whether marveling at species like the "shaggy rose goblet" and "dead man''s fingers," or getting to know the miraculous forms that take root in the backyard, readers will come to rely on this work of remarkable breadth, depth, and elegance. Created by the worldÂ’s most trusted name in nature field guides, this handsome volume is the result of a collaboration among leading scientists, scholars, taxonomic and field experts, photo editors, and designers. An indispensable resource, with nearly 2,900 full-color photographs, it reveals the astounding variety of forms, colors, and conditions of 668 species of mushrooms that can be found all throughout North America.For ease of use, the book includes a glossary, an index, and a ribbon marker, and is organized according to the latest phylogenetic arrangement from the Assembling the Fungal Tree of Life project. Each species features up to five vibrant photographs, to aid with identification, along with notes on range, season, spore print, ... Unknown localization key: "more"

Objev podobné jako National Audubon Society Mushrooms of North America - National Audubon Society National Audubon Society

The most comprehensive and authoritative guide to the wildflowers of North America, updated for the first time in decades to reflect the impact of climate change and the advancements in DNA studies that have radically altered the classification process.Whether preparing for a scenic hike or getting to know the flowers in the backyard, readers will come to rely on this work of remarkable breadth, depth, and elegance. This handsome volume, from the world''s most trusted name in nature field guides, is the result of a collaboration among leading scientists, scholars, taxonomic and field experts, photo editors, and designers. An indispensable resource, it covers 853 species of wildflowers, with nearly 5,200 full-color photographs.For ease of use, the book includes a glossary, an index, and a ribbon marker, and is organized according to the latest Angiosperm Phylogeny Group IV classification system. Each species features up to five vibrant photographs, to aid with identification, along with notes on range, season, flowers, stems, fruit, conservation status, and more. Introductory essays give in-depth explanations of each part of a wildflower, and discuss nomenclature, invasive species, and the impacts of our changing climate.Whether preparing for a scenic hike or getting to know the flowers in the ... Unknown localization key: "more"

Objev podobné jako National Audubon Society Wildflowers of North America - National Audubon Society National Audubon Society

Practical and portable, this is the ultimate field guide for any whale-watcher in North America

Objev podobné jako Field Guide to Whales, Dolphins and Porpoises of North America - Mark Carwardine

A guide to the lichens of North America, presenting colour photographs, descriptions, distribution maps and keys for identification. It focuses on 805 foliose, fruticose and crustose lichens and covers another 700 species in the keys or notes. English names are provided for most species.

Objev podobné jako Lichens of North America - Irwin M. Brodo, Sylvia Duran Sharnoff, Stephen Sharnoff

Tapping into the resurgence of interest in mythology and illustrated with 75 linocut-style artworks, this contemporary, cool and highly desirable collection of North American folktales has standout visual appeal.

Objev podobné jako Frightful Folklore of North America - Mike Bass

The most user-friendly butterfly guide ever published, still handy and compact. - Includes color plates of Mexican-border rarities - More than 2,300 images of butterflies in natural poses - Pictorial table of contents - Convenient one-page index - Range maps on text pages

Objev podobné jako Kaufman Field Guide To Butterflies Of North America - Kenn Kaufman, Jim P. Brock

Publisher''s Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.WHAT''S IN STICK AND RUDDER:The invisible secret of all heavier-than-air flight: the Angle of Attack. What it is, and why it can''t be seen. How lift is made, and what the pilot has to do with it.Why airplanes stall How do you know you''re about to stall?The landing approach. How the pilot''s eye functions in judging the approach.The visual clues by which an experienced pilot unconsciously judges: how you can quickly learn to use them."The Spot that does not move." This is the first statement of this phenomenon. A foolproof method of making a landing approach across pole lines and trees.The elevator and the throttle. One controls the speed, the other controls climb and descent. Which is which?The paradox of the glide. By pointing the nose down less steeply, you descend more steeply. By pointing the nose down more steeply, you can glide further.What''s the rudder for? The rudder does NOT turn the airplane the way a boat''s rudder turns the boat. Then what does it do?How a turn is flown. The role of ... Unknown localization key: "more"

Objev podobné jako Stick and Rudder: An Explanation of the Art of Flying - Wolfgang Langewiesche

An investigative history course directly accessible to all pupils at Key Stage 3.

Objev podobné jako Native Peoples of North America - Susan Edmonds

Based on vivid and illuminating ethnographic research from both east and west Europe, this book investigates the relationship between geopolitical and physical borders and ideological, classificatory boundaries, highlighting bordering process, and showing how the two often operate in tandem in the regulation of reproduction, care and intimacy. -- .

Objev podobné jako Intimacy and Mobility in an Era of Hardening Borders

A startling collection of stories from a debut British writer.

Objev podobné jako An Account of the Decline of the Great Auk, According to One Who Saw It - Jessie Greengrass

Plakát Call of Duty Sunset využívá lentikulární tisk k vytvoření 3D efektu s proměnou obrazu. Výrobek je opatřen plastovým profilovým rámem a očkem pro zavěšení. Rozměry plakátu jsou 28 × 24 × 4 cm.

• Lentikulární tisk vytváří živý 3D efekt a proměnu obrazu
• Kvalitní plastový profilový rám pro stabilní uchycení
• Licenční motiv Call of Duty pro fanoušky herní série
• Praktické očko na zadní straně pro snadné zavěšení

Objev podobné jako 3D Obraz Call of Duty Sunset

Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, from cardiovascular disease to cancer to AIDS. Based on the authorsÂ’ collective experiences in this field, Introduction to Statistical Methods for Clinical Trials presents various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. After reviewing the history, ethics, protocol, and regulatory issues of clinical trials, the book provides guidelines for formulating primary and secondary questions and translating clinical questions into statistical ones. It examines designs used in clinical trials, presents methods for determining sample size, and introduces constrained randomization procedures. The authors also discuss how various types of data must be collected to answer key questions in a trial. In addition, they explore common analysis methods, describe statistical methods that determine what an emerging trend represents, and present issues that arise in the analysis of data. The book concludes with suggestions for reporting trial results that are consistent with universal guidelines recommended by medical journals. Developed from a course taught at the University of Wisconsin for the past 25 years, this textbook provides a solid understanding of the statistical approaches used in ... Unknown localization key: "more"

Objev podobné jako Introduction to Statistical Methods for Clinical Trials

A classic field guide to these well-loved birds, updated with the latest taxonomical information. Nothing says spring to a birder like seeing the flash of bright plumage as a warbler, recently arrived from its southern wintering grounds, flits from branch to branch, hunting for insects. Eastern North America is home to over 40 species of warblers, and Warblers of Eastern North America is the essential guidebook to identifying and enjoying the huge range of species that live in this area of the continent. With over 240 crisp, full-color photographs and precise identification notes, Warblers of Eastern North America is indispensable to naturalists, students and birders of all levels of experience. Author and naturalist Chris G. Earley''s concise and well-organized text gives the reader pointers on identification - including male and female differences, seasonal plumages, distinctive markings, song descriptions and cheat sheets. The book also features range maps for each described species, charts showing the seasonal status of the warblers, and photographic comparison charts that group similar-looking birds on a single page for quick reference. Here are just a handful of the species profiled in Warblers of Eastern North America: Tennessee Warbler Cerulean Warbler Chestnut-sided Warbler Painted Redstart Yellow-rumped Warbler Blackburnian ... Unknown localization key: "more"

Objev podobné jako Warblers of Eastern North America - Chris G Earley

The incredible untold origin story of cyberwar and the hackers who unleashed it on the world, tracing their journey from the ashes of the Cold War to the criminal underworld, governments, and even Silicon Valley. Two years before 9/11, the United States was attacked by an unknown enemy. No advance warning was given, and it didn't target civilians. Instead, tomahawk missiles started missing their targets, US agents were swept up by hostile governments, and America’s enemies seemed to know its every move in advance. A new phase of warfare—cyber war—had arrived. And within two decades it escaped Pandora's Box, plunging us into a state of total war where every day, countless cyber attacks perpetrated by states and mercenaries are reshaping the world. After receiving an anonymous email with leaked NATO battle plans during the bombardment of Kosovo, journalist Matt Potter embarked on a twenty-year investigation into the origins of cyber war and how it came to dominate the world. He uncovered its beginnings – worthy of a Bond movie – in the last days of the Cold War, as the US and its allies empowered a generation of Eastern European hackers, only to wake up in the late 90s to ... Unknown localization key: "more"

Objev podobné jako We Are All Targets : How Renegade Hackers Invented Cyber War and Unleashed an Age of Global Chaos

Figurka - herní set, postavička, sběratelská, motiv The Last of Us - Part II, výška 18 cm, materiál plast, s pohyblivými končetinami, vhodná od 16 let Zásadní přednosti figurky The Last of Us Part II - Joel and Ellie - figurka Figurka NECA nadchne každého sběratele Je ideální pro děti od 16 let Figurka ze série The Last of Us - Part II vyniká kvalitním zpracováním Materiálem využitým při výrobě je plast U hraní se dětem jistě budou líbit pohyblivé končetiny Součástí balení jsou 2 figurky Figurka NECA měří 18 cm

Objev podobné jako The Last of Us Part II - Joel and Ellie - figurka (634482444900)

This volume surveys the archaeology of Native North Americans from their arrival on the continent 15,000 years ago up to contact with European colonizers. Offering rich descriptions of monumental structures, domestic architecture, vibrant objects, and spiritual forces, Timothy R. Pauketat and Kenneth E. Sassaman show how indigenous people shaped both their history and North America''s many varied environments. They place the student in the past as they trace how Native Americans dealt with challenges such as climate change, the rise of social hierarchies and political power, and ethnic conflict. Written in a clear and engaging style with a compelling narrative, The Archaeology of Ancient North America presents the grand historical themes and intimate stories of ancient Americans in full, living color.

Objev podobné jako The Archaeology of Ancient North America - Kenneth E. Sassaman, Timothy R. Pauketat

The book reviews the recent research advances and their outcomes in the areas of structural biology, bioinformatics, phytochemistry and drug discovery. Chapters in the book cover multidisciplinary research to understand the molecular mechanisms involved in protein-protein/ligand interactions. It employs an integrative approach to identify the therapeutic targets for HIV, and cancer, pathogen and viral infection pathways and the identification of their potential drug candidates. The book also provides examples of computational molecular dynamics simulations to understand the conformational changes in the molecules. Some chapters are focused on exploring potent bioactive compounds from natural sources.This book can serve as a single source that covers several interdisciplinary research fields which will be beneficial to Researchers and students in postgraduate studies.

Objev podobné jako Therapeutic Protein Targets For Drug Discovery And Clinical Evaluation: Bio-crystallography And Drug Design

A new edition of the best-selling field guide with 25 all-new plates covering the birds of Hawaii. For decades, the Peterson Field Guide to Birdsof Western North America has been a popular and trusted guide for birders of all levels, thanks to its famous system of identification and unparalleled illustrations. Following the Spring 2020 update to Peterson Field Guide to Birds of North America, this guide will feature updated text and range maps, and art updated to reflect current knowledge in ornithology. Now that the American Birding Association has expanded its species Checklist to include Hawaii, this guide will include 25 all-new plates covering the birds of Hawaii.

Objev podobné jako Peterson Field Guide To Birds Of Western North America, Fifth Edition - Roger Tory Peterson

The Handbook of Intellectual Disability and Clinical Psychology Practice will equip clinical psychologists in training with the skills necessary to complete a clinical placement in the field of intellectual disability. Building on the success of the previous edition this handbook has been extensively revised. Throughout, the text, references, and website addresses and have been updated to reflect important developments since the publication the first edition. Recent research findings on the epidemiology, aetiology, course, outcome, assessment and treatment of all psychological problems considered in the book have been incorporated into the text. Account has been taken of changes in the diagnosis and classification of intellectual disability and psychological problems reflected in the AAIDD-11 and the DSM-5. New chapters on the assessment of adaptive behaviour and support needs, person-centred active support, and the assessment of dementia in people with intellectual disability have been added.The book is divided into eight sections:Section 1: Covers general conceptual frameworks for practice - diagnosis, classification, epidemiology and lifespan development.Section 2: Focuses on assessment of intelligence, adaptive behaviour, support needs, quality of life, and the processes of interviewing and report writing. Section 3: Covers intervention frameworks, specifically active support, applied behavioural analysis and cognitive behaviour therapy.Section 4: Deals ... Unknown localization key: "more"

Objev podobné jako The Handbook of Intellectual Disability and Clinical Psychology Practice

Figurka - soška, postavička, sběratelská, výška 20 cm, materiál plast, nepohyblivá Figurka ze hry The Last of Us Part II zobrazuje hlavní postavu Ellie s lukem připraveným ke střelbě. Vznikla spoluprací firmy Naughty Dog, která figurku navrhla. Prototyp vytvořila Gentle Giant Studios a o finální produkci se postarala Dark Horse. Figurka z druhé části hry The Last of Us je velmi autentická a propracovaná do detailů. Je vyrobena z PVC a stojí na kulaté základně s logem hry. Klíčové vlastnosti figurky The Last of Us Part II - Ellie with BowFigurka pro fanoušky druhé části hry The Last of UsZobrazuje hlavní postavu Ellie s lukem připraveným ke střelběFigurka The Last of Us Part II je vyrobena z PVCNa jejím vzniku se podílely firmy Dark Horse, Naughty Dog a Gentle Giant StudiosStojí na kulaté základně s logem hryJe vhodná pro kluky i holkyVýška figurky:20 cm

Objev podobné jako The Last of Us Part II - Ellie with Bow - figurka (761568006735)

Figurka - soška, postavička, sběratelská, motiv The Last of Us - Part II, výška 20 cm, materiál plast, nepohyblivá, vhodná od 3 let Zásadní vlastnosti figurky The Last of Us Part II - Joel - figurka Figurka Dark Horse bude pěkným dárkem pro sběratele Je určena pro ratolesti od 3 let Figurka ze série The Last of Us - Part II se bude vyjímat ve sbírce díky svému kvalitnímu zpracování Materiálem využitým při výrobě je plast The Last of Us Part II - Joel - figurka poslouží jako dekorace V balení obdržíte jednu figurku Figurka Dark Horse měří 20 cm

Objev podobné jako The Last of Us Part II - Joel - figurka (761568009255)

Figurka - soška, postavička, sběratelská, motiv The Last of Us - Part II, výška 20 cm, materiál plast, nepohyblivá, vhodná od 3 let Hlavní přednosti figurky The Last of Us Part II - Abby - figurka Figurka Dark Horse přinese radost sběratelům Je určena pro děti od 3 let Figurka ze série The Last of Us - Part II se bude vyjímat ve sbírce díky svému kvalitnímu zpracování Materiálem využitým při výrobě je plast The Last of Us Part II - Abby - figurka představuje dekorativní sošku V balení obdržíte jednu figurku Figurka Dark Horse měří 20 cm

Objev podobné jako The Last of Us Part II - Abby - figurka (761568009248)

The only portable full-color photographic guide to the most commonly seen bees east of the Mississippi RiverBees play a vitally important role in the pollination of native plants and agricultural crops around the globe. Common Bees of Eastern North America is the first species-level photographic field guide to the most commonly seen bees in the eastern United States and Canada. Identifying bees to species is challenging even for taxonomists. This book walks you through the process of bee identification using breathtaking high-resolution color photos that highlight the unique characteristics of each species, making identification easier. Full of essential facts about the natural history of these magnificent creatures, this is the must-have field guide for naturalists and backyard gardeners alike.Covers 125 of the most commonly seen species in the eastern United States and CanadaFeatures 500 stunning close-up photos in full colorShows multiple images for each species, with arrows highlighting key identifying marksProvides silhouette images depicting the actual size of each speciesDescribes key identification features, size, phenology, floral preference, nesting, and related speciesIncludes a range map for every speciesContains a taxonomic key to the bee genera of the eastern United States and Canada

Objev podobné jako Common Bees of Eastern North America - Joseph S. Wilson, Olivia Messinger Carril

The fundamental, one-stop global resource for neurosurgical practice in updated 10th edition Unlike traditional medical textbooks, the origins of the now legendary Handbook of Neurosurgery by Mark Greenberg took root in the late 1980’s in the notes the author kept while taking care of his patients, from his weekly grand rounds presentations, and in the literature he read. Now in its 10th edition, the book that is often referred to as the “bible for neurosurgeons” has grown organically over the years to include more topics of importance to those who provide healthcare to patients with neurologic ailments, and to reflect advances in the understanding and management of the underlying conditions and diseases. Throughout 23 sections and 116 chapters, the generously illustrated text covers information ranging from pediatrics to geriatrics. The comprehensive, conveniently compact book provides detailed, high-value, and actionable information that can be quickly accessed to enhance patient management, thereby eliminating the need to wade through superfluous material. It is also a perfect study companion for board examination and preparation for the maintenance of certification. Key Features Updated classification and diagnostic criteria of central and peripheral nervous system tumors, based on the most recent WHO classificationsReworking of numerous sections, including ... Unknown localization key: "more"

Objev podobné jako Greenberg's Handbook of Neurosurgery - Mark S. Greenberg

`the state of men without civil society (which state we may properly call the state of nature) is nothing else but a mere war of all against all.'' Thomas Hobbes was the first great philosopher to write in English. His account of the human condition, first developed in The Elements of Law (1640), which comprises Human Nature and De Corpore Politico, is a direct product of the intellectural and political strife of the seventeenth century. It is also a remarkably penetrating look at human nature, and a permanently relevant analysis of the fears of self-seeking that result in the war of `each against every man''. In The Elements of Law Hobbes memorably sets out both the main lines of his general philosophy, later augmented in De Corpore (1655), and the moral and political philosophy later made famous in Leviathan (1651). Copies of Human Nature and De Corpore Politico, until 1889 printed as separate works, are rare antiques or scarcely less rare scholarly texts; this is the first complete popular edition. It is here supplemented by chapters from De Corpore and Three Lives, two from Hobbes''s original Latin. These have never before been published together in English. ABOUT THE SERIES: For ... Unknown localization key: "more"

Objev podobné jako The Elements of Law Natural and Politic. Part I: Human Nature; Part II: De Corpore Politico - Thomas Hobbes

Cornwall’s rugged coast is etched with stories. Here you’ll find tales of powerful mermaids, spiteful witches, crafty smugglers and woeful ghosts. Up on the moors are mischievous creatures, huge giants and elusive beasts. Let the piskeys lead you astray across the windy tors and sandy shorelines to experience wonder, miracles, secrets and magic. Bodmin Moor folklore writer Anna Chorlton retells tales of North and East Cornwall, illustrated by local artists and members of the community.

Objev podobné jako Cornish Folk Tales of Place: Traditional Stories from North and East Cornwall - Anna Chorlton

Beginning with an overview of Judaism in North America, this book presents a survey of the tradition, provides historical context, and addresses key contemporary issues. It covers the essential topics in the study of Judaism in North America including the major texts of Judaism, the Jewish life cycle, rabbinic literature, and the Jewish calendar.Key topics include Jewish identity and diversity, how Americans perceive Jews, and the rise of the Jewish GenZ. With over 50 illustrations throughout, each chapter contains suggested further reading and a glossary of key terms and concepts.The chapters in this book were first published in the digital collection Bloomsbury Religion in North America. Covering North America’s diverse religious traditions, this digital collection provides reliable and peer-reviewed articles and ebooks for students and instructors. Learn more and get access for your library at www.theologyandreligiononline.com/bloomsbury-religion-in-north-america

Objev podobné jako Judaism in North America

Hudební CD - Lords of Black je španělská heavy metalová skupina a její album Alchemy of Souls Part II. je v pořadí čtvrté. Lords of Black je španělská heavy metalová skupina a její album Alchemy of Souls Part II. je v pořadí čtvrté. Rok vydání : 2021 Seznam stop CD Prelude (Alchimia Confessio 1458 A.D.) / Maker Of Nothingness / What's Become Of Us / Bound To You / Before That Time Can Come / Mind Killer / Death Dealer / Prayers Turned To Whispers / In A Different Light / How Long Do I Have Now / Fated To Be Destroyed / No Hero Is Homeless / Sympathy

Objev podobné jako Lords Of Black: Alchemy of Souls Part II. - CD (8024391115824)

Hra na konzoli - PS4 / PS4 Pro, PS5 (s mechanikou), krabicová verze, české titulky, žánr: akční, - Prožij stále intenzivnější morální rozpory, které na Ellie působí vlivem její nelítostné honby za pomstou. Kolotoč násilí, který za sebou zanechává, otřese tvou představou o rozlišování správného od špatného, dobra od zla a hrdinů od padouchů. The Last of Us Part II PS4 otestuje vaše limityProžijte na vlastní kůži pokračování jednoho z nejvýraznějších příběhů herní historie. Vžijte se opět do mladičké Ellie přežívající ve smrtícím postapokalyptickém světě, který jí nutí k činům, nad nimiž se vám bude tajit dech. Co vše dokážete pro to, abyste zůstali další den naživu? Objevujte padlý svět v The Last of Us Part IIV The Last of Us Part II PS4 Navštívíte Zemi po událostech, jež jí změnily k nepoznání. Putujte kdysi životem pulzujícími dopravními...

Objev podobné jako The Last of Us Part II - PS4 (PS719331001)

Follow Ellie''s profound and harrowing journey of vengeance through an exhaustive collection of original art and intimate creator commentary in the full-color hardcover volume: The Art of The Last of Us Part II. Created in collaboration between Dark Horse Books and the developers at Naughty Dog, The Art of The Last of Us Part II offers extensive insights into the making of the long-awaited sequel to the award-winning The Last of Us.

Objev podobné jako The Art of The Last of Us Part II - Naughty Dog Studios

A look at North Korea''s secretive military detailing its unique weaponry, doctrines, and modernization efforts.Modernity has lifted the obsessive veil of secrecy in military innovation in all but one country: North Korea. With both its past and present a mystery, there exists little reliable information on one of the most exotic armed forces in the world today. Having essentially run aground its entire economy for the twin purposes of Juche (self-reliance) and Songun (military first), the DPRK today fields a uniquely diverse inventory of indigenous weaponry, and adheres to a military doctrine unlike any other. This highly unconventional situation is simultaneously one of the most precarious in the world, with the possibility of conflict ever looming on the horizon. To many, North Korea has become synonymous with the threat of nuclear war, having seen ballistic missiles soar and the ground tremble under a succession of escalating strategic weapons tests. The international focus on this topic has resulted in an imbalance of information, where its equally significant and numerically vast conventional forces are typically ignored. More than just posing a threat in its immense proportions however, the KPA remains a force to reckoned with due to a continuing drive for modernization, ... Unknown localization key: "more"

Objev podobné jako The Armed Forces of North Korea Volume 1 Part 1 - Joost Oliemans, Stijn Mitzer