chemistry at the service of medicine erik de clercq
Chemistry at the Service of Medicine - Erik De Clercq
Proč přesně, chemie a medicína? Autor této knihy, prof. Erik De Clercq, ve svých přednáškách představuje nádherný svět na pomezí (bio)chemie a moderní medicíny. Zdůraznil například biosyntézu nukleotidů, porfyrinů, hemu, hemoglobinu, cholesterolu, žlučových kyselin, CO, NO, roli karboxylových kyselin, močoviny a dalších cyklů, patologii diabetu, dny a dalších metabolických onemocnění, roli enzymů, hormonů, vitamínů, antibiotik a antivirotik. Cílem celého pojednání je okouzlit čtenáře bez ohledu na věk či původ krásou (bio)chemie při dobývání lidského zdraví. Why precisely, chemistry and medicine? Author of this book, Prof. Erik De Clercq, in his lectures presents a wonderful world on the border of (bio)chemistry and modern medicine. He has highlighted, for instance, the biosynthesis of nucleotides, porphyrins, heme, hemoglobine, cholesterol, bile acids, CO, NO, the role of the carboxylic acids, urea and other cycles, the pathology of diabetes, gout and other metabolic diseases, the role of enzymes, hormones, vitamins, antibiotics and antivirals. The aim of the whole treatise is to enchant the readers, whatever their age or background, with the beauty of (bio)chemistry at the conquest of human health.
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The Organic Chemistry of Biological Pathways - John E. McMurry
The Organic Chemistry of Biological Pathways was written for an audience of advanced undergraduates and graduate students who want a deeper understanding of the chemical reactions that take place in living organisms. The authors assume readers have a background in organic chemistry at the level of the typical two-semester college course. Although enzymes are crucial to biological reactions, the authors’ focus always remains on the reactivity patterns of the substrate molecules and on the organic, arrow-pushing details of the individual reactions.The authors begin the book with a brief review chapter on the fundamental organic reaction mechanisms commonly found in biochemical pathways. Following this brush up on reaction mechanisms is a general introduction to the main classes of biomolecules. Then comes the heart of the book: full chapters devoted to the major metabolic pathways of the main classes of biomolecules—lipids, carbohydrates, proteins, nucleotides, and secondary metabolites. In the course of these chapters, readers cover the chemistry of the common coenzymes, see examples of the common sorts of biological transformations, and ultimately begin to develop an understanding of the patterns found throughout bioorganic chemistry. The authors conclude with a summary of the reaction patterns and mechanisms frequently used in nature to effect ... Unknown localization key: "more"
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Confessions of an English Opium Eater - Thomas de Quincey
A masterpiece of autobiography, and perhaps the first literary memoir of an addict, the Penguin Classics edition of Thomas De Quincey''s Confessions of an English Opium-Eater is edited with an introduction by Barry Milligan.Confessions is a remarkable account of the pleasures and pains of worshipping at the ''Church of Opium''. Thomas De Quincey consumed daily large quantities of laudanum (at the time a legal painkiller), and this autobiography of addiction hauntingly describes his surreal visions and hallucinatory nocturnal wanderings through London, along with the nightmares, despair and paranoia to which he became prey. The result is a work in which the effects of drugs and the nature of dreams, memory and imagination are seamlessly interwoven, describing in intimate detail the mind-altering pleasures and pains unique to opium. Confessions of an English Opium-Eater forged a link between artistic self-expression and addiction, paving the way for later generations of literary addicts from Baudelaire to James Frey, and anticipating psychoanalysis with its insights into the subconscious.This edition is based on the original serial version of 1821, and reproduces two ''sequels'', ''Suspiria de Profundis'' (1845) and ''The English Mail-Coach'' (1849). It also includes a critical introduction discussing the romantic figure of the addict and ... Unknown localization key: "more"
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The Art Deco Style - Alastair Duncan
This grand opus assembles the people and the pieces at the heart of the Art Deco movement at each stage of its enduring appeal. The Art Deco Style is richly illustrated with the work of legendary designers and decorators Eileen Gray, Paul Iribe, Antoine Bourdelle, Armand-Albert Rateau and Jean Dunand, among others.   Ever since its early 20th-century origins, Art Deco has fascinated and amused socialites, collectors and designers. Referred to at the time as moderne, the style largely took shape around a clientele of French fashion industry luminaries and wealthy international collectors. Art historians christened it during a second wave in the ’60s, while a third generation of afficionados entered the auction houses of the ’80s and ’90s, ready to invest in the most exquisite examples. Curated by art consultant and author Alastair Duncan, this detailed historical account is the gold-standard visual guide to the decorative arts.   Â
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Curiosities in Medicine - Achim Langenbucher, Sibylle Scholtz, Myriam Becker, Lee MacMorris
This anthology is devoted to the curious side of Medical History. Carl Sagan said: ”You have to know the past to understand the present.” This collection of 80 short stories, written by experts in the field, inspires curiosity and provides a detailed look at the History of Medicine.It investigates many topics, including ancient Egyptian knowledge, the fundamental importance of toothache and how it birthed Anesthesia, and why and when women were allowed to run marathons. The authors report on the background of rubber gloves, the stethoscope and the intraocular lens. Historically important biographies are included, such as those of Arthur Conan Doyle, Napoleon Bonaparte and Claude Monet.The book is relevant for those interested in Medicine and its curious history.Â
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Tamil Tigress - Niromi de Soyza
How was it that this well-educated, mixed-race, middle-class girl from a respectable family came to be fighting with the Tamil Tigers? Two days before Christmas in 1987, at the age of seventeen, Niromi de Soyza found herself in an ambush as part of a small platoon of militant Tamil Tigers fighting government forces in the bloody civil war that was to engulf Sri Lanka for decades. With her was her lifelong friend Ajanthi, also aged seventeen. Leaving behind them their shocked middle-class families, the teenagers had become part of the Tamil Tigers'' first female contingent. Equipped with little more than a rifle and a cyanide capsule each, Niromi''s group managed to survive on their wits in the jungle, facing not only the perils of war but starvation, illness and growing internal tensions among the militant Tigers. But then events erupted in ways that she could no longer bear.
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In The Garden of Beasts - Erik Larson
''A compelling tale... a narrative that makes such a brave effort to see history as it evolves and not as it becomes.'' SPECTATORSuffused with the tense atmosphere of the times, and with brilliant portraits of Hitler, Goebbels, Goering and Himmler amongst others, Erik Larson''s new book sheds unique light on events as they unfold, resulting in an unforgettable, addictively readable work of narrative history.Berlin,1933. William E. Dodd, a mild-mannered academic from Chicago, has to his own and everyone else''s surprise, become America''s first ambassador to Hitler''s Germany, in a year that proves to be a turning point in history. Dodd and his family, notably his vivacious daughter, Martha, observe at first-hand the many changes - some subtle, some disturbing, and some horrifically violent - that signal Hitler''s consolidation of power. Dodd has little choice but to associate with key figures in the Nazi party, his increasingly concerned cables make little impact on an indifferent U.S. State Department, while Martha is drawn to the Nazis and their vision of a ''New Germany'' and has a succession of affairs with senior party players, including first chief of the Gestapo, Rudolf Diels. But as the year darkens, Dodd and his daughter find their ... Unknown localization key: "more"
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The Demon of Unrest - Erik Larson
#1 NEW YORK TIMES BESTSELLER The author of The Splendid and the Vile brings to life the pivotal five months between the election of Abraham Lincoln and the start of the Civil War in this ''riveting reexamination of a nation in tumult'' (Los Angeles Times).On November 6, 1860, Abraham Lincoln became the fluky victor in a tight race for president. The country was bitterly at odds; Southern extremists were moving ever closer to destroying the Union, with one state after another seceding and Lincoln powerless to stop them. Slavery fuelled the conflict, but somehow the passions of North and South came to focus on a lonely federal fortress in Charleston Harbor: Fort Sumter.Master storyteller Erik Larson offers a gripping account of the chaotic months between Lincoln’s election and the Confederacy’s shelling of Sumter – a period marked by tragic errors and miscommunications, enflamed egos and craven ambitions, personal tragedies and betrayals. Lincoln himself wrote that the trials of these five months were ‘so great that, could I have anticipated them, I would not have believed it possible to survive them’.At the heart of this suspense-filled narrative are Major Robert Anderson, Sumter’s commander and a former slave owner sympathetic to the ... Unknown localization key: "more"
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The Reformations of Medicine - Ekaterina N. Lomperis
The sixteenth century witnessed unprecedented reformations in both religious belief and medical knowledge, marked by the rise of Protestantism, the Catholic reform movement, and the new approaches to the study of human anatomy, laying the groundwork for the emergence of evidence-based medicine. The Reformations of Medicine investigates the transformations of religious perspectives on medicine and healing during this era, with a particular focus on Martin Luther''s thought. Lomperis explores the implications of these early modern developments for current intersections of spirituality and healthcare.The study reveals how early Protestants reimagined the spiritual significance of medicine. It illuminates previously little-studied aspects of Luther''s theological thought concerning physical suffering. Lomperis argues that Luther pursued a spiritual reformation of approaches to medicine and healing, informed by his theology of created means and idolatry. She demonstrates that Luther''s theology challenged the long-standing tradition of viewing natural healing through medicine as spiritually inferior to supernatural, divine healing.Lomperis develops strategies utilizing early modern thought as a resource for navigating the complexities of suffering in contemporary medical contexts, addressing religiously motivated suspicion of scientific medicine, and engaging Christian spiritualities of healing to promote more equitable healthcare systems.With rigorous historical research and erudite contemporary analysis, this book provides an ... Unknown localization key: "more"
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The end of medicine as we know it - and why your health has a future - Harald H.H.W. Schmidt
Medicine itself is sick. We hardly understand any disease and therefore need to chronically treat symptoms but not the causes. Consequently, drugs and other therapies help only very few patients; yet we are pumping more and more money into our healthcare system without any added value.Thus, the internationally renowned physician researcher, Harald Schmidt, predicts the end of medicine as we know it. On a positive note, digitization will radically change healthcare and lead to one of the greatest socioeconomic revolutions of mankind. He is one of the pioneers of "systems medicine", a complete redefinition of what we actually call a "disease", how we organize medicine and how we use Big Data to heal rather than treat, to prevent rather than cure. In this book the author first proves the deep crisis of medicine, but describes how medicine will become more precise, more uniform, safer and, surprisingly, also more affordable. Making a diagnosis will be taken over by artificial intelligence. Current, mainly organ-based medical specialists, disciplines and hospital departments will disappear. Physicians will become patient coaches working in interdisciplinary teams with pharmacists, physiotherapists, nutritionists, etc. and relieved of their workload. Illnesses, including cancer, will be prevented or cured in a precise ... Unknown localization key: "more"
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The Rise and Fall of the House of Medici - Christopher Hibbert
At its height Renaissance Florence was a centre of enormous wealth, power and influence. A republican city-state funded by trade and banking, its often bloody political scene was dominated by rich mercantile families, the most famous of which were the Medici. This enthralling book charts the family’s huge influence on the political, economic and cultural history of Florence. Beginning in the early 1430s with the rise of the dynasty under the near-legendary Cosimo de Medici, it moves through their golden era as patrons of some of the most remarkable artists and architects of the Renaissance, to the era of the Medici Popes and Grand Dukes, Florence’s slide into decay and bankruptcy, and the end, in 1737, of the Medici line.
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The Invention of Medicine
Longlisted for the RUNCIMAN AWARD, 2021Medicine is one of the great fields of achievement of the Ancient Greeks. Hippocrates is celebrated worldwide as the father of medicine and the Hippocratic Oath is admired throughout the medical profession as a founding statement of ethics and ideals. In the fifth century BC, Greeks even wrote of medicine as a newly discovered craft they had invented.Robin Lane Fox''s remarkable book puts their invention of medicine in a wider context, from the epic poems of Homer to the first doctors known to have been active in the Greek world. He examines what we do and do not know about Hippocrates and his Oath and the many writings that survive under his name. He then focuses on seven core texts which give the case histories of named individuals, showing that books 1 and 3 belong far earlier than previously recognised. Their re-dating has important consequences for the medical awareness of the great Greek dramatists and the historians Herodotus and Thucydides. Robin Lane Fox pieces together the doctor''s thinking from his terse observations and relates it in a new way to the history of Greek prose and ideas.This original and compelling book opens windows onto many ... Unknown localization key: "more"
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The History of Medicine - William Bynum
Against the backdrop of unprecedented concern for the future of health care, this Very Short Introduction surveys the history of medicine from classical times to the present. Focussing on the key turning points in the history of Western medicine, such as the advent of hospitals and the rise of experimental medicine, Bill Bynum offers insights into medicine''s past, while at the same time engaging with contemporary issues, discoveries, and controversies.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
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The Language of Medicine - Abraham Fuks
Language exercises a powerful impact on medical care as the words that physicians use with patients have the power to heal or harm. The practice of medicine is shaped by the potent metaphors that are prevalent in clinical care, especially military metaphors and the words of war that bring with them unfortunate consequences for patients and physicians alike. Physicians who fight disease turn the patient into a passive battlefield. Patients are encouraged to remain stoic, blamed for "failing" chemotherapy and sadly remembered in heroic obituaries of lost battles. The search for disease as enemy shifts the doctor''s gaze to the computer and imaging technologies that render the patient transparent, unseen and unheard. Modern treatments save lives but patients can be the victims of collateral damage and friendly fire. In The Language of Medicine, Abraham Fuks, physician, medical educator, and former Dean of Medicine at McGill University, shows us how words are potent drugs that must be tailored to the individual patient and applied in carefully chosen and measured doses to offer benefits and avoid toxicity. The book shines a light on our culture that deprecates the skill of listening that is, paradoxically, the attribute that patients most desire of their ... Unknown localization key: "more"
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Mitochondria and the Future of Medicine - Lee Know
Dr. Lee Know does a brilliant job shedding light on this once ignored organelle and shows us how to care for our most important metabolic system. Dr. Nasha Winters, co-author of The Metabolic Approach to CancerFrom infertility to aging to cancer and neurological disease, Dr. Lee Know will teach you that mitochondria play a central role in much that we care about in health and disease. Stephanie Seneff, senior research scientist, MITÂ Â Why do we age? Why does cancer develop? What''s the connection between heart failure and Alzheimer''s disease or infertility and hearing loss? Can we extend lifespan and if so, how? What is the Exercise Paradox? Why do antioxidant supplements sometimes do more harm than good? Many will be amazed to learn that all these questions, and many more, can be answered by a single point of discussion: mitochondria and bioenergetics.In Mitochondria and the Future of Medicine, Naturopathic Doctor Lee Know tells the epic story of mitochondria, the widely misunderstood and often-overlooked powerhouses of our cells. The legendary saga began over two billion years ago, when one bacterium entered another without being digested which would evolve to create the first mitochondrion. Since then, for life to exist beyond ... Unknown localization key: "more"
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The History of Medicine in Twelve Objects - Carol Cooper
Discover the fascinating history of medicine from its primitive beginnings to the lifesaving technologies of today.Award-winning author Dr Carol Cooper takes you on a journey through the 12 objects that have come to define medicine through the ages – from the barbaric and bizarre to the inventive and impressive, this captivating read is peppered with fascinating anecdotes.In this unique history, you will discover how ill health has been with us for as long as humans have existed, as has the drive to treat and understand it. Over the course of centuries, the ways in which doctors have engaged with sickness has changed drastically, and so too have the tools at their disposal.And as these tools have morphed and evolved, our knowledge of health and disease has expanded. Medical theories have slowly advanced, allowing people to live longer and healthier lives.The 12 groundbreaking tools explored in this collection include:THE TREPHINETHE BONE SAWTHE MASKTHE MICROSCOPETHE STETHOSCOPETHE ETHER INHALERTHE HYPODERMIC SYRINGETHE OBSTETRIC FORCEPSTHE X -RAY MACHINETHE ECT MACHINETHE HIP PROSTHESISTHE HEART-LUNG MACHINEThe history of these medical tools is truly astounding, revealing the true extent of human ingenuity, curiosity, and compassion. This is a book for anyone interested in medical history or looking for ... Unknown localization key: "more"
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The Fighter of Auschwitz - Erik Brouwer
The story of Dutch boxer Leen Sanders who was spared to entertain the Nazi guards and helped others survive Auschwitz.'He had the dream again last night... He taps the gloves of his unbeaten Polish opponent. There are rumours that the loser will be sent to the gas chamber.' In 1943 Leen Sanders, Dutch champion boxer, was sent to Auschwitz. His wife and children were put to death while he was sent 'to the left' with the others fit enough for labor. Recognised by an SS officer, he was earmarked for a 'privileged' post in the kitchens in exchange for weekly boxing matches for the entertainment of the Nazi guards. From there, he enacted his resistance to their limitless cruelty. With great risk and danger to his own life, Leen Sanders stole, concealed and smuggled food and clothing from SS nursing units for years to alleviate the unbearable suffering of the prisoners in need. He also regularly supplied extra food to the Dutch women in Dr. Mengele's experiment Block 10. To his fellow Jews in the camp, he acted as a rescuer, leader and role model, defending them even on their bitter death march to Dachau towards the end of the ... Unknown localization key: "more"
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General Chemistry: The Essential Concepts - Raymond Chang, Kenneth Goldsby
The seventh edition of General Chemistry continues the tradition of presenting only the material that is essential for a one-year general chemistry course. It strikes a balance between theory and application by incorporating real-world examples; helping students visualize the three-dimensional atomic and molecular structures that are the basis of chemical activity; and developing problem-solving and critical thinking skills. Although the seventh edition incorporates many impressive features, such as conceptual idea review, animations correlated to the text, and hand-sketched worked examples, General Chemistry is still 200 to 300 pages shorter and much less expensive than other two-semester textbooks. Dr. Chang and Dr. Goldsby’ concise-but-thorough approach will appeal to efficiency-minded instructors and value-conscious students.
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The Demon of Unrest - Erik Larson
#1 NEW YORK TIMES BESTSELLER The author of The Splendid and the Vile brings to life the pivotal five months between the election of Abraham Lincoln and the start of the Civil War in this 'riveting reexamination of a nation in tumult' (Los Angeles Times).
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Data and Metrics for the DOD SBIR and STTR Programs - Engineering, and Medicine National Academies of Sciences, Policy and Global Affairs, Technology,
In response to a congressional mandate, a committee of the National Academies of Sciences, Engineering, and Medicine is conducting a review of the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs at the Department of Defense (DOD). These programs, created in 1982 and 1992, respectively, and operated within the DOD and a number of other agencies within the federal government, encourage the participation by small business concerns in the federal research and development and procurement processes through competitively based awards. As part of its review of the DOD's SBIR/STTR programs, and in response to a request by the DOD, the present study committee held a workshop on December 7-8, 2023, entitled "Data and Metrics for the DOD SBIR and STTR Programs." The workshop was convened to facilitate the DOD's development of recurring, quantifiable metrics for measuring the ability of the SBIR and STTR programs to deliver products and services that meet the DOD's mission needs, while also informing the National Academies committee's overall study of the programs at the DOD. This proceedings of a workshop was prepared by a workshop rapporteur as a factual summary of what was presented and discussed at the workshop.
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The Book of Hops - Erik Christiansen, Dan Disorbo
The first fully illustrated guidebook for craft beer drinkers, pairing hyper-detailed photography with profiles of 50 of todayÂ’s most popular hop varieties.Hops are the most important ingredient in the beer we love, offering a spectrum of distinct aromas, flavors, and bitterness. Whether itÂ’s a floral Cascade, spicy Saaz, juicy Citra, or a combination of different varieties, hop character has become the driving force behind craft brewing. The Book of Hops profiles fifty of the most sought-after hops from around the world, with intricate photography and notes on taste, composition, use, and origin, plus examples of the wonderful beers that showcase them. With contributions from todayÂ’s most important brewers and growers; a handy primer that breaks down the science, story, and production of beer; and hand-picked craft beer recommendations throughout, this fully illustrated guidebook is all you need to discover and fully savor your next favorite brew.
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The Art of Theatre - Erik Ramsey, Wright, William, Jr. Downs
THE ART OF THEATRE: THEN AND NOW, 4th Edition, brings the fascinating world of theatre to life with lively coverage of the history, cultural diversity, creativity, controversy -- and even a typical day in the life -- of theatre. As the authors wrote each chapter, they asked themselves how the subject applies to students'' lives. The result is a text packed with practical information you can use in everyday life, including insight on censorship, freedom of speech, copyrights, the National Endowment for the Arts, and more. Timely connections drawn between theatre and TV and film help you see how the living stage is unique, and the optional MindTap digital learning solution provides a variety of online study tools to help you ensure your success in the course.
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The Reality of Being - Jeanne de Salzmann
An important book on liberating ourselves from the state of “waking sleep” in which we live our lives, as taught by one of the most influential spiritual teachers of the 20th century As the closest pupil of the charismatic spiritual master G. I. Gurdjieff (1866–1949), Jeanne de Salzmann was charged with carrying on his teachings of spiritual transformation. Known as the Fourth Way or “The Work,” Gurdjieff’s system was based on teachings of the East that he adapted for modern life in the West. Now, some twenty years after de Salzmann''s death, the notebooks that she filled with her insights over a forty-year period (and intended to publish) have been translated and edited by a small group of her family and followers. The result is this long-awaited guide to Gurdjieff''s teaching, describing the routes to be traveled and the landmarks encountered along the way. Organized according to themes, the chapters touch on all the important concepts and practices of the Work, including:• Awakening from the sleep of identification with the ordinary level of being• Self-observation and self-remembering• Conscious effort and voluntary suffering• Understanding symbolic concepts like the Enneagram• The Gurdjieff Movements, bodily exercises that provide training in Presence and the ... Unknown localization key: "more"
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The Story of Babar - Jean de Brunhoff
“If you love elephants, you will love Babar and Celeste,… writes A. A. Milne, author of Winnie-the-Pooh, in his preface to The Story of Babar. “And if you have never loved elephants, you will love them now.…"After his mother is killed by a hunter, Babar avoids capture by escaping to the city, where he is befriended by the kindly Old Lady. He becomes educated and cultured and, upon his return to the great forest, is crowned King of the Elephants.Jean de Brunhoff’s tales of Babar have charmed readers around the world for 80 years. His stories have followed the king of the elephants as he builds a city, founds a family and even meets Father Christmas. Tested by difficult trials – from snakes to fire to runaway prams – he always comes out on top, with the help of patience, determination and, on one memorable occasion, a flight of winged elephants. One of the most iconic series of animal books in history, Babar has become a household name both as a character in children’s books and on TV.Beautifully illustrated, this edition is an ideal gift for children aged 3 and up.Also look out for The Babar Collection and Babar the ... Unknown localization key: "more"
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The Beauty of Falling - Claudia de Rham
A world-renowned physicist seeks gravity’s true nature and finds wisdom in embracing its force in her lifeClaudia de Rham has been playing with gravity her entire life. As a diver, experimenting with her body’s buoyancy in the Indian Ocean. As a pilot, soaring over Canadian waterfalls on dark mornings before beginning her daily scientific research. As an astronaut candidate, dreaming of the experience of flying free from Earth’s pull. And as a physicist, discovering new sides to gravity’s irresistible personality by exploring the limits of Einstein’s general theory of relativity. In The Beauty of Falling, de Rham shares captivating stories about her quest to gain intimacy with gravity, to understand both its feeling and fundamental nature. Her life’s pursuit led her from a twist of fate that snatched away her dream of becoming an astronaut to an exhilarating breakthrough at the very frontiers of gravitational physics. While many of us presume to know gravity quite well, the brightest scientists in history have yet to fully answer the simple question: what exactly is gravity? De Rham reveals how great minds—from Newton and Einstein to Stephen Hawking, Andrea Ghez, and Roger Penrose—led her to the edge of knowledge about this fundamental force. ... Unknown localization key: "more"
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Social Chemistry : Decoding the Patterns of Human Connection - King Marissa
Conventional wisdom would have us believe that it is the size of your network that matters: how many people do you know? We're told to mix, mingle, and connect.But social science research suggests otherwise.The quality and structure of our relationships have far greater impact on our personal and professional lives. our relationships with friends, family, co-workers, neighbours, and collaborators are by far our greatest asset. Yet, most people leave them to chance.In this ground-breaking study, Marissa King, Professor of Organizational Behavior at the Yale, argues that there are strategic ways in which we can alter our relationships for a happier and more fulfilling life. With new understanding, this book can help readers to see how they can harness the power of their networks in their personal relationships, at work, and to create a better world.
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The Course of Love - Alain de Botton
SUNDAY TIMES TOP TEN BESTSELLERFrom one of our great thinkers on modern life and the human condition - an unforgettable story of love and marriage from the author of bestselling novel Essays in Love as well as The Consolations of Philosophy, Religion for Atheists and The School of Life''The Course of Love probes the very heart of marriage, its shifts and squalls, its great adventure, with such forensic tenderness. I laughed a lot, too'' Deborah MoggachModern love is never easy. Society is obsessed with stories of romance, but what comes after happily ever after?This is a love story with a difference. From dating to marriage, from having kids to having affairs, it follows the progress of a single ordinary relationship: tender, messy, hilarious, painful, and entirely un-Romantic. It is a love story for the modern world, chronicling the daily intimacies, the blazing rows, the endless tiny gestures that make up a life shared between two people. Moving and deeply insightful, The Course of Love offers us a window into essential truths about the nature of love.''Engaging, sympathetic, acutely perceptive... There''s a refreshing honesty in what de Botton has to say'' Guardian''Anyone who is, has been, or would ever like to ... Unknown localization key: "more"
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The Art of Travel - Alain de Botton
THE SUNDAY TIMES TOP TEN BESTSELLER''Honest, funny and dripping with witty aphorisms. Extremely entertaining and enlightening [...] all the way to journey''s end'' Herald One of our greatest voices in modern philosophy, author of The Course of Love, The Consolations of Philosophy, Religion for Atheists and The School of Life, presents a travel guide with a difference - an exploration of why we travel, and what we learn along the way...Few activities seem to promise as much happiness as going travelling: taking off for somewhere else, somewhere far from home, a place with more interesting weather, customs and landscapes. But although we are inundated with advice on where to travel to, we seldom ask why we go and how we might become more fulfilled by doing so.With the help of a selection of writers, artists and thinkers - including Flaubert, Edward Hopper, Wordsworth and Van Gogh - Alain de Botton provides invaluable insights into everything from holiday romance to hotel minibars, airports to sightseeing. The perfect antidote to those guides that tell us what to do when we get there, The Art of Travel tries to explain why we really went in the first place - and helpfully suggest how ... Unknown localization key: "more"
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The Best of Everything - Kit de Waalová
From the author of My Name is Leon comes an unforgettable story of found family and the love that steals into our lives... in spite of our best laid plans.''Tender. Beautifully judged'' Guardian ''I read this in a sitting, revelling in every word-perfect sentence'' (reader review) ⭐ ⭐ ⭐ ⭐ ⭐ ''De Waal takes an ordinary life and renders it extraordinary'' Monica Ali ''A beautiful and important story about kindness that will break your heart, then make it sing'' (reader review) ⭐ ⭐ ⭐ ⭐ ⭐ ''Wonderful. De Waal writes brilliantly about forgiveness'' Clare Chambers ''A profoundly compassionate novel of devastating power'' Bernardine Evaristo Paulette''s the kind of woman who likes the future all mapped out: the wedding to Denton, the Caribbean honeymoon, the gingham quilt on the baby''s crib. Until one morning Garfield, Denton''s friend, arrives at her door with the news that Denton won''t be coming around any more, that there won''t be time for her to say goodbye. Somehow Garfield finds his way into her bed, and sooner than anyone can believe there is a baby, and suddenly giving Bird, her son, the best of everything is what gives Paulette''s life meaning. So why is it another ... Unknown localization key: "more"
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The Prime of Life - Simone de Beauvoirová, Peter Green
The second volume in Simone de Beauvoir’s celebrated autobiography recalls her formative years in Paris when she began to emerge as a public figureFirst published in 1960, The Prime of Life offers an intimate, captivating picture of Simone de Beauvoir in her twenties, thirties and forties. Beginning as a recent graduate from the Sorbonne teaching high-school girls, we see de Beauvoir revel in the freedom her new financial independence brings. We see her and Jean-Paul Sartre recognise the powerful romantic and intellectual partnership they have found in one another, as they fall in love and define their own unconventional parameters. The Second World War comes, bringing austerity, violence and questions of the reality of freedom and individual responsibility into de Beauvoir’s life. As relevant and penetrating as when first published, The Prime of Life offers rare insight into a truly fascinating mind.
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Petrucci's General Chemistry: Principles and Modern Applications - Carey Bissonnette, Ralph Petrucci, Jeffry Madura, F. Herring
The most trusted general chemistry text is back in a thoroughly revised 12th edition. Petrucci''s General Chemistry: Principles and Modern Applications is written for students who have already studied some chemistry. Students with no prior background and those who could use a refresher will find that the early chapters develop fundamental concepts from the most elementary ideas. Students who plan to become professional chemists will also find opportunities in the text to pursue their own special interests. Petrucci''s General Chemistry: Principles and Modern Applications is recognized for its superior problems, lucid writing, precision of argument, and meticulous treatment of the subject. The 12th edition offers enhanced hallmark features, new innovations, and revised discussions that respond to key market needs for the detailed and modern treatment of chemistry, embracing the power of visual learning and conquering the challenges of effective problem solving and assessment. In every explanation, illustration, and media resource, students and instructors benefit from the care and craftsmanship of an extraordinarily talented and collaborative authorial team who shared a wealth of experience from regularly teaching a general chemistry course for majors as well as non-majors. Also Available with Mastering™ Chemistry This title is also available with Mastering Chemistry—an online ... Unknown localization key: "more"
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The Perils of Lady Catherine de Bourgh - Claudia Gray
The third book in the Mr. Darcy & Miss Tilney Mystery series, which finds the amateur sleuths facing their most daunting challenge yet: preventing the murder of the imperious Lady Catherine de Bourgh.Someone is trying to kill Lady Catherine de Bourgh. Esteemed aunt of Mr. Fitzwilliam Darcy, generous patroness of Mr. William Collins, a woman of rank who rules over the estate of Rosings Park with an unimpeachable sense of propriety—who would dare? Lady Catherine summons her grand-nephew, Mr. Jonathan Darcy, and his investigative companion, Miss Juliet Tilney, to find out.After a year apart, Jonathan and Juliet are thrilled to be reunited, even if the circumstances—finding whoever has thus far sabotaged Lady Catherine''s carriage, shot at her, and nearly pushed her down the stairs—are less than ideal. Also less than ideal: their respective fathers, Mr. Fitzwilliam Darcy and Mr. Henry Tilney, have accompanied the young detectives to Rosings, and the two men do not interact with the same felicity enjoyed by their children.With attempts against Lady Catherine escalating, and no one among the list of prime suspects seemingly capable of committing all of the attacks, the pressure on Jonathan and Juliet mounts—even as more gentle feelings between the two of ... Unknown localization key: "more"
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The Last Murder at the End of the World - Stuart Turton
''Absolutely unforgettable'' READER REVIEW ''Unlike anything I''ve ever read before'' READER REVIEWTHE NUMBER ONE SUNDAY TIMES BESTSELLEROn a mysterious island where crime does not exist, a seemingly impossible murder has been committed…. Can you join together with a very unlikely amateur detective to solve the Last Murder at the End of the World?The small group of villagers who live on the tiny island lead simple, but happy lives. There is no world beyond their shores, but they’re content with what they have. Only Emory feels frustrated. Unlike everyone else on the island she doesn’t yet seem to have a purpose. All she seems to be good at is asking questions.But then one of the scientists who guides the villagers is found murdered and as there has never been a crime before, there is no detective to call on. There is only Emory and her gift for asking questions. So now Emory must explore every inch of her island – from the cliffs to the jungles, from sandy beaches to the very top of the mountain – to find clues that apparently don’t exist. How can she solve a mystery on an island where no one lies but there’s still no ... Unknown localization key: "more"
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Chemistry - Peter Atkins
Most people remember chemistry from their schooldays as largely incomprehensible, a subject that was fact-rich but understanding-poor, smelly, and so far removed from the real world of events and pleasures that there seemed little point, except for the most introverted, in coming to terms with its grubby concepts, spells, recipes, and rules. Peter Atkins wants to change all that. In this Very Short Introduction to Chemistry, he encourages us to look at chemistry anew, through a chemist''s eyes, in order to understand its central concepts and to see how it contributes not only towards our material comfort, but also to human culture. Atkins shows how chemistry provides the infrastructure of our world, through the chemical industry, the fuels of heating, power generation, and transport, as well as the fabrics of our clothing and furnishings. By considering the remarkable achievements that chemistry has made, and examining its place between both physics and biology, Atkins presents a fascinating, clear, and rigorous exploration of the world of chemistry - its structure, core concepts, and exciting contributions to new cutting-edge technologies. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized ... Unknown localization key: "more"
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The Blood of Others - Simone de Beauvoirová
Potent and vividly emotional, Simone de Beauvoir’s captivating novel questions freedom and individual responsibility in the face of brutality‘These carefree faces, on which we allowed our smiles to spread, were for others the mask of tragedy.’Jean Blomart, patriot leader against the German forces of occupation, waits throughout an endless night for his wounded lover, Hélène, to die. Told through memories of his and her life, The Blood of Others paints an intense and moving picture of their love story and life in German occupied Paris during the Second World War. In the face of a seemingly unstoppable force, Hélène and Jean are confronted by the illusion of freedom and made to question their individual roles in the collective struggle against fascism, with devastating consequences.First published in 1945, this powerful novel resonates profoundly today and brings the ideas of one of the most important existentialist thinkers to life in spellbinding prose.With an Introduction by Ali Smith.
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The Ocean at the End of the Lane - Neil Gaiman
A special Christmas edition of the Sunday Times bestseller.WINNER OF THE SPECSAVERS NATIONAL BOOK AWARDS 2013 BOOK OF THE YEARThe Ocean at the End of the Lane is the bestselling magical novel from Neil Gaiman, one of the most brilliant storytellers of our generation and author of the epic novel American Gods, and the much-loved Sandman series. ''Possibly Gaiman''s most lyrical, scary and beautiful work yet. It''s a tale of childhood for grown-ups, a fantasy rooted in the darkest corners of reality'' (Independent on Sunday). If you loved the mesmerising world of Erin Morgenstern''s The Night Circus or were drawn into J.K. Rowling''s magical universe, this book is for you. It began for our narrator forty years ago when the family lodger stole their car and committed suicide in it, stirring up ancient powers best left undisturbed. Dark creatures from beyond this world are on the loose, and it will take everything our narrator has just to stay alive: there is primal horror here, and menace unleashed - within his family and from the forces that have gathered to destroy it. His only defence is three women, on a farm at the end of the lane. The youngest of them ... Unknown localization key: "more"
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The Age of Empathy - Frans de Waal
''Kindness and co-operation have played a crucial role in raising humans to the top of the evolutionary tree ... We have thrived on the milk of human kindness.'' ObserverBY THE AUTHOR OF ARE WE SMART ENOUGH TO KNOW HOW SMART ANIMALS ARE?''There is a widely-held assumption that humans are hard-wired for relentless and ruthless competition ... Frans de Waal sees nature differently - as a biological legacy in which empathy, not mere self-interest, is shared by humans, bonobos and animals.'' Ben Macintyre, The TimesEmpathy holds us together. That we are hardwired to be altruistic is the result of thousands of years of evolutionary biology which has kept society from slipping into anarchy. But we are not alone: primates, elephants, even rodents are empathetic creatures too.Social behaviours such as the herding instinct, bonding rituals, expressions of consolation and even conflict resolution demonstrate that animals are designed to feel for each other. From chimpanzees caring for mates that have been wounded by leopards, elephants reassuring youngsters in distress and dolphins preventing sick companions from drowning, with a wealth of anecdotes, scientific observations, wry humour and incisive intelligence, The Age of Empathy is essential reading for all who believe in the power of ... Unknown localization key: "more"
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At the End of Everything - Nijkamp Marieke
From the #1 New York Times bestselling author of This Is Where It Ends comes another heartbreaking, emotional and timely page-turner that will keep you on the edge of your seat. The Hope Juvenile Treatment Center is ironically named. No one has hope for the delinquent teenagers who have been exiled there; the world barely acknowledges that they exist. Then the guards at Hope start acting strange. And one day…they don't show up. But when the teens band together to make a break from the facility, they encounter soldiers outside the gates. There's a rapidly spreading infectious disease outside, and no one can leave their houses or travel without a permit. Which means that they're stuck at Hope. And this time, no one is watching out for them at all. As supplies quickly dwindle and a deadly plague tears through their ranks, the group has to decide whom among them they can trust – and figure out how they can survive in a world that has never wanted them in the first place. Gripping, emotional and fiercely compelling, At the End of Everything is a powerful exploration of societal neglect and the resilience of the human spirit in the face ... Unknown localization key: "more"
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Murder at the Tower of London - Jim Eldridge
London, 1899. A shocking murder is discovered at the heart of the Tower of London. The dead body of a Yeoman Warder is found inside a suit of armour belonging to Henry VIII, having been run through with a sword, and when details of this outrage are reported to the Prince of Wales, he fears this may be an expression of Republican unrest striking at the very home of the Crown Jewels. In the hopes of hampering the spread of news about the crime, the Prince reluctantly calls upon the services of Daniel Wilson and Abigail Fenton, the museum detectives, to investigate further. As their inquiries proceed, Wilson and Fenton learn about the long and bloody history of the Tower of London, but dark deeds are not confined to the Tower''s shadowy past. More bones will see the light of day and the twists and turns of a dastardly plot will unravel before the museum detectives'' case is closed. The ninth in the massively popular series of crime novels set behind the scenes at England''s most celebrated museums and beloved attractions including The Ashmolean, The British Museum and The Natural History Museum The protagonist is the detective who led the ... Unknown localization key: "more"
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At the Mountains of Madness - Howard P. Lovecraft, Francois Baranger
Arkham, 1933. Professor Dyer, a prominent geologist, learns that a scientific expedition will soon leave for Antarctica following in the footsteps of the journey which he himself had made in 1931. In the hope of dissuading the attempt, Dyer decides to make a full account of the tragic events he had survived, this time without omitting the passages which he had kept silent about on his return, for fear of being taken for a madman. Two years earlier, ships chartered by Miskatonic University had landed on the frozen continent at the start of the Antarctic summer, and the group of four professors and sixteen students set to work immediately. The expedition biologist, Professor Lake, left with several members of the team to follow a promising fossil track. After just a few days, he announced by radio that he had discovered astonishing specimens of an unknown ancient species, before stopping all communication after a terrible storm. Guessing the worst, Dyer went to their rescue the next day. What he discovered went beyond his wildest fears ...In the illustrated AT THE MOUNTAINS OF MADNESS VOL.1, artist, Francois Baranger, acclaimed for his work as a concept designer for cinema and video games, has ... Unknown localization key: "more"
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In the Service of the Sultan: A First Hand Account of the Dhofar Insurgency - Ian Gardiner
Tells the largely unknown story of a small number of British officers who led Muslim soldiers in this hard-fought anti-insurgency war. After outlining the historical, geographical and political background, this book describes military action, including operations with irregular forces and the SAS as well as action in the air and at sea.
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Maths for Chemistry - Lindsey Munro, Paul Monk
Mathematical skills and concepts lie at the heart of chemistry, yet they are the aspect of the subject that many students fear the most.Maths for Chemistry recognizes the challenges faced by many students in equipping themselves with the maths skills necessary to gain a full understanding of chemistry. Working from foundational principles, the book builds the student''s confidence by leading them through the subject in a steady, progressive way from basic algebra to the mathematics of quantum chemistry.Opening with the core mathematics of algebra, logarithms and trigonometry, the book goes on to cover calculus, matrices, vectors, complex numbers, and laboratory mathematics to cover everything that a chemistry student needs. With its modular structure, the book presents material in short, manageable sections to keep the content as accessible and readily digestible as possible. Maths for Chemistry is the perfect introduction to the essential mathematical concepts which all chemistry students should master.
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All the Frequent Troubles of Our Days : The True Story of the American Woman at the Heart of the German Resistance to Hitler
The INSTANT New York Times BestsellerWinner of the National Book Critics Circle Award for Biography Winner of the PEN/Jacqueline Bograd Weld Award Winner of the Chautauqua Prize Finalist for the Los Angeles Times Book Award Finalist for the Plutarch AwardA New York Times Notable Book of 2021A New York Times Book Review Editors' Choice A New York Times Critics' Top Pick of 2021Wall Street Journal 10 Best Books of 2021Time Magazine 100 Must-Read Books of 2021Publishers Weekly Top Ten Books of 2021 An Economist Best Book of the Year A New York Post Best Book of the Year A Milwaukee Journal Sentinel Best Book of the YearOprah Daily Best New Books of AugustA New York Public Library Book of the Week In this “stunning literary achievement,” Donner chronicles the extraordinary life and brutal death of her great-great-aunt Mildred Harnack, the American leader of one of the largest underground resistance groups in Germany during WWII—“a page-turner story of espionage, love and betrayal” (Kai Bird, winner of the Pulitzer Prize for Biography) Born and raised in Milwaukee, Mildred Harnack was twenty-six when she enrolled in a PhD program in Germany and witnessed the meteoric rise of the Nazi party. In 1932, she ... Unknown localization key: "more"
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Cold For The Bastards Of Pizzofalcone - Maurizio de Giovanni
Cold winds, political hijinks, and murder on the streets of Naples.A heinous, double murder in a squalid apartment on the wrong side of town pits Inspector Lojacono, Di Nardo and the rest of the motley collection of cops known as the “bastards†of the Pizzofalcone precinct against their superiors, the press, and the local political hierarchy. Only by bringing the killer to justice can they save their reputations and the department.De Giovanni is one of the most versatile, prolific, and successful European mystery in Europe. His award-winning and bestselling novels, all set in Naples, offer a brilliant vision of the criminal underworld and the lives of the cops in Europe’s most fabled, atmospheric, dangerous, and lustful city.
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H.P. Lovecraft's At the Mountains of Madness Volume 1 (Manga) - Gou Tanabe
From adapter and illustrator Gou Tanabe, comes H.P Lovecraft''s At the Mountains of Madness. This manga adaptation of some of Lovecraft''s best stories is perfect for manga fans and Lovecraft fans alike. With art resembling more of a western comic book, this book lends itself well as a ''gateway'' for those who are looking to get into manga!January 25, 1931: an expedition team arrives at a campsite in Antarctica...to find its crew of men and sled dogs strewn and dead. Some are hideously mangled, as if in rage--some have been dissected in a curious and cold-blooded manner. Some are missing. But a still more horrific sight is the star-shaped mound of snow nearby...for under its five points is a grave--and what lies beneath is not human!At the Mountains of Madness is a journey into the core of Lovecraft''s mythos--the deep caverns and even deeper time of the inhospitable continent where the secret history of our planet is preserved--amidst the ruins of its first civilization, built by the alien Elder Things with the help of their bioengineered monstrosities, the shoggoths. Since it was first published in Astounding Stories during the classic pulp era, At the Mountains of Madness has influenced both ... Unknown localization key: "more"
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The Caravan at the Edge of Doom: Foul Prophecy - Jim Beckett
Hilarious sequel to The Caravan at the Edge of Doom, perfect for fans of Terry Pratchett, David Walliams and Roald Dahl!Twelve-year old Harley is happy to be back home after her adventures in the Land of the Dead. But strange things soon start happening. A bunch of Restless Souls turn up in at school, the portal of doom breaks AND everyone thinks Harley has blown up her best friend Bess. Is this all connected to a mysterious ancient prophecy that everyone in the Land of the Dead keeps talking about…? There’s only one thing for it. Harley has to unleash her inner Legendary Hero and head Beyond Life for more monsters, mysteries and mayhem!This must-read sequel to the The Caravan at the Edge of Doom is full of heart, humour and heroism.
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The Boy At the Back of the Class - Onjali Q. Rauf
WINNER OF THE BLUE PETER BOOK AWARD (UK) 2019 WINNER OF THE WATERSTONES CHILDREN''S BOOK PRIZE (UK) 2019 WINNER OF THE SAKURA MEDAL (JAPAN) 2020 WINNER OF THE CHILDREN''S COWBELL AWARD (SWITZERLAND) 2021 WINNER OF THE PRIX JANUSZ KORCZAK PRIZE (FRANCE) 2022 ''There used to be an empty chair at the back of my class, but now a new boy called Ahmet is sitting in it. He''s a refugee who''s run away from a War. A real one. With bombs and fires and bullies that hurt people. And the more I find out about him, the more I want to help ... That''s where my best friends Josie, Michael and Tom come in. Because you see, together we''ve come up with a plan...''On a perfectly ordinary school day, something extraordinary happens: a boy with pale skin, lion eyes and a tattered red rucksack walks in. Unable to speak English and seated at the back of the class, Ahmet ''the refugee kid'' becomes the perfect target for bullies and rumours alike.But Ahmet has also captured the attention and empathy of a fellow classmate, who will do anything to help him find his family. Even if that involves a plan - or ... Unknown localization key: "more"
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The School of Life - Alain de Botton
The essential guide to how to live wisely and well in the twenty-first century - from Alain de Botton, the bestselling author of The Consolations of Philosophy, The Art of Travel and The Course of LoveThis is a book about everything you were never taught at school. It's about how to understand your emotions, find and sustain love, succeed in your career, fail well and overcome shame and guilt. It's also about letting go of the myth of a perfect life in order to achieve genuine emotional maturity. Written in a hugely accessible, warm and humane style, The School of Life is the ultimate guide to the emotionally fulfilled lives we all long for - and deserve.
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The Gift of Fear - Gavin de Becker
In this empowering book, Gavin de Becker, the man Oprah Winfrey calls the US' leading expert on violent behaviour, shows you how to spot even subtle signs of danger - before it's too late. Shattering the myth that most violent acts are unpredictable, de Becker, whose clients include top Hollywood stars and government agencies, offers specific ways to protect yourself and those you love, including: how to act when approached by a stranger; when you should fear someone close to you; what to do if you are being stalked; how to uncover the source of anonymous threats or phone calls; the biggest mistake you can make with a threatening person; and more. You can learn to spot the danger signals others miss.It might just save your life.
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The Mushroom at the End of the World - Anna Lowenhaupt Tsing
"A poetic and remarkably fertile exploration of the relationship between human beings and the natural environment."—Pankaj Mishra, The Guardian"I'm very grateful to have this book."—Ursula K. Le GuinThe acclaimed and award-winning book about what a rare mushroom can teach us about sustaining life on a fragile planetA Flavorwire and Times Higher Education Book of the YearMatsutake is the most valuable mushroom in the world—and a weed that grows in human-disturbed forests across the northern hemisphere. Through its ability to nurture trees, matsutake helps forests to grow in daunting places. It is also an edible delicacy in Japan, where it sometimes commands astronomical prices. In all its contradictions, matsutake offers insights into areas far beyond just mushrooms and addresses a crucial question: what manages to live in the ruins we have made? A tale of diversity within our damaged landscapes, The Mushroom at the End of the World follows one of the strangest commodity chains of our times to explore the unexpected corners of capitalism. Here, we witness the varied and peculiar worlds of matsutake commerce: the worlds of Japanese gourmets, capitalist traders, Hmong jungle fighters, industrial forests, Yi Chinese goat herders, Finnish nature guides, and more. These companions also lead ... Unknown localization key: "more"
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